Prescribing information

 

The below content is for healthcare professionals in Great Britain only. If you require information for Northern Ireland please refer to the Northern Ireland prescribing information.

 

Prescribing information

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HCP downloadable resources

Explore our growing repository of resources designed to provide useful information on SCEMBLIX and other relevant topics for healthcare professionals treating patients with CML.

 

SCEMBLIX MOA video

A video displaying the mechanism of action of SCEMBLIX, the first and only STAMP inhibitor, specifically targeting the ABL myristoyl pocket.1–3

Picture of patient support booklet

Support booklet for patients on SCEMBLIX

This downloadable PDF can be shared with patients prescribed Scemblix with CP Ph+ CML, to provide further information about their condition and useful advice about taking SCEMBLIX.

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Support groups for your patients

 

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CML, chronic myeloid leukaemia; MOA, mechanism of action; STAMP, specifically targeting the ABL1 myristoyl pocket.

SCEMBLIX is indicated for the treatment of adult patients with Philadelphia chromosome-positive chronic myeloid leukaemia (Ph + CML) in chronic phase (CP), previously treated with two or more tyrosine kinase inhibitors, and without a known T315I mutation.4

For further information please refer to the Summary of Product Characteristics.

 

References

  1. Réa D, et al. Blood 2021;138(21):2031–2041.
  2. Redaelli S, et al. J Clin Oncol 2009;27(3):469–471.
  3. Schoepfer J, et al. J Med Chem 2018;61(18):8120–8135.
  4. SCEMBLIX (asciminib) Summary of Product Characteristics.
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UK | October 2022 | 212225

Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard. Adverse events should also be reported to Novartis via uk.patientsafety@novartis.com or online through the pharmacovigilance intake (PVI) tool at www.novartis.com/report
If you have a question about the product, please contact Medical Information on 01276 698370 or by email at medinfo.uk@novartis.com